Luigi Mangione, the 26-year-old Ivy League graduate charged in connection with the murder of UnitedHealthcare CEO Brian Thompson, has two sisters, the physician MariaSanta Mangione and the artist Luciana Mangione.
On Monday, Luigi Mangione was arrested in Altoona, Pennsylvania, after being recognized at a McDonald’s restaurant, police said. He was subsequently arraigned in a Pennsylvania court and denied bail. Hours later, New York investigators added five charges, including murder.
Thompson was shot dead outside the Hilton in midtown Manhattan on Wednesday by a masked attacker using a silencer in what police said was likely a “premeditated, preplanned, targeted attack.” According to reports, the words “deny,” “delay” and “depose” were found written on three bullet cases at the scene.
Altoona Police Department/GETTY
In a statement posted on social media by Luigi Mangione’s cousin, Maryland House Delegate Nino Mangione, the family said: “Unfortunately, we cannot comment on news reports regarding Luigi Mangione. We only know what we have read in the media.
“Our family is shocked and devastated by Luigi’s arrest. We offer our prayers to the family of Brian Thompson and we ask people to pray for all involved. We are devastated by this news.”
Newsweek contacted MariaSanta Mangione for comment on Tuesday via LinkedIn outside regular office hours and Luciana Mangione via Instagram and X.
Who Is MariaSanta Mangione?
MariaSanta Mangione works as a physician at the University of Texas Southwestern, according to her profile on Vanderbilt University’s website. She studied at Vanderbilt from 2012 to 2020, her LinkedIn profile said, and completed a Ph.D. in cell and developmental biology.
Prior to her graduate studies, she completed her undergraduate degree at the University of Maryland, where she studied cell biology and molecular genetics, according to her LinkedIn profile.
On Google Scholar, MariaSanta Mangione is cited as a co-author of several publications, including the 2019 paper “Molecular Form and Function of the Cytokinetic Ring”—a structure that forms during cell division—and 2023’s “Efficacy of Bortezomib Desensitization Among Heart Transplant Candidates.” In total, papers she co-authored have been cited 147 times by other scholars, the website showed.
On Instagram, MariaSanta Mangione appears to have used the handle @gabymzayas, which has since been deleted. X user @evollive said MariaSanta Mangione shared a photograph of an “Annual Holiday Party” on Monday, shortly before the account was deactivated. Newsweek has not independently verified the authenticity of this post.
The physician’s Vanderbilt University page links to the X account @msm128, which has also been deleted.
Who Is Luciana Mangione?
Luciana Mangione is an artist who previously worked in the retail grocery industry, according to a September profile by the online media publication VoyageBaltimore.
Speaking to the publication, she said, “I attended the College of Charleston where I majored in International Business and minored in Studio Art and Italian Language.”
She added, “I also worked in art galleries in Charleston, SC and in Florence, Italy during my time in college.”
After graduating, Luciana Mangione worked on “retail operations, merchandising and supply chain,” she told the outlet. In 2023, she had a daughter and “decided to pursue a career in painting professionally.”
Luciana Mangione has been linked on social media to the @lifewithlu_ accounts on Instagram and X, both of which have been set to private.
According to Olivia Reingold, a reporter at the Free Press, on Monday, the @lifewithlu_ Instagram account posted a picture of Luciana Mangione and Luigi Mangione in swimwear, with the caption, “Praying for you @luigi.from.fiji.”
